Dr
Christopher
Tynan
Link Scientist at Octopus Facility
(01235) 567089
No
christopher.tynan@stfc.ac.uk
No
RAL R92,1.16
No
No

​​​​​Research interests

Investigating how signal transduction by the Epidermal Growth Factor Receptor family of tyrosine kinase receptors is regulated by their conformation, their interactions with each other and also with constituents of the cell membrane and cytoplasmic molecules. Studying the relationship between deregulation of these signals and disease (e.g. cancer) and elucidating the effects of therapeutic drugs targeted to these receptors at the molecular level. Single molecule tracking of membrane proteins, Forster Resonance Energy Transfer as a tool for measuring intermolecular distances and super-resolution microscopy of cell and tissue samples.

Background

PhD, University of Liverpool. ‘A quantitative Förster resonance energy transfer method reveals functionally relevant structural variations in ErbB transmembrane receptors in cells’.

General

Chris has been a member of the LSF since 2008 and is currently a postdoctoral research assistant for the BBSRC LoLa grant, Supra-molecular rules in signalling networks: A single molecule comparative study in cells and tissues